ABSTRACT

Primary localized cutaneous amyloidosis (PCA) is a rare disorder characterized by amyloid deposition in dermis without systemic involvement. There are three different types of primary localized cutaneous amyloidosis: Lichen amyloidosis, macular amyloidosis and nodular amyloidosis. The lesions of lichen amyloidosis are characterized by pruritic papules. Although, topical or intralesional treatment with corticosteroids, topical dimethyl sulfoxide, ultraviolet B, oral psoralen plus ultraviolet A, retinoic acid derivatives are the recommended treatment for lichen amyloidosis, the results are often unsatisfactory. In the literature, there have been only a few reports evaluating the efficacy of low dose acitretin in the treatment of lichen amiloidosis. In this article, we report a case of lichen amyloidosis with pruritic hyperkeratotic papules on the back and chest of 5 years’ duration, successfully treated with low dose acitretin.